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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPTE
All Species:
21.21
Human Site:
Y393
Identified Species:
46.67
UniProt:
P56180
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P56180
NP_954868.1
551
64306
Y393
K
T
P
S
Q
K
R
Y
V
A
Y
F
A
Q
V
Chimpanzee
Pan troglodytes
XP_509584
486
53797
M337
A
A
N
M
G
T
P
M
M
P
D
N
G
A
V
Rhesus Macaque
Macaca mulatta
XP_001082960
622
70709
I421
L
L
V
D
V
I
Y
I
F
F
D
I
K
F
L
Dog
Lupus familis
XP_848413
692
79416
Y540
E
T
P
S
Q
N
R
Y
V
G
Y
F
A
D
V
Cat
Felis silvestris
Mouse
Mus musculus
NP_954866
664
76687
Y513
E
T
P
S
Q
N
R
Y
V
K
Y
F
E
K
L
Rat
Rattus norvegicus
NP_001102347
673
77862
Y516
E
T
P
S
Q
N
R
Y
V
K
Y
F
E
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513133
495
57137
K346
V
G
Y
F
E
V
I
K
N
K
Y
K
W
N
L
Chicken
Gallus gallus
XP_417079
511
58892
Y357
E
T
P
S
Q
S
R
Y
V
G
Y
Y
E
I
L
Frog
Xenopus laevis
NP_001090072
509
58511
Y356
E
T
P
S
Q
S
R
Y
V
A
Y
Y
E
V
L
Zebra Danio
Brachydanio rerio
NP_001020629
511
58583
Y357
E
T
P
S
Q
S
R
Y
V
G
Y
Y
E
I
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788391
351
40843
G202
E
Q
V
K
F
K
Y
G
G
Q
I
P
E
P
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
26.3
20.1
49.4
N.A.
50.1
50
N.A.
48.4
49.5
49.3
47.1
N.A.
N.A.
N.A.
N.A.
32.6
Protein Similarity:
100
38.8
35.3
61.4
N.A.
63.4
63.4
N.A.
63.3
65.3
65.1
63.8
N.A.
N.A.
N.A.
N.A.
44.1
P-Site Identity:
100
6.6
0
73.3
N.A.
60
60
N.A.
6.6
53.3
60
53.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
13.3
6.6
80
N.A.
80
80
N.A.
20
73.3
80
73.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
0
0
0
0
0
19
0
0
19
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
0
19
0
0
10
0
% D
% Glu:
64
0
0
0
10
0
0
0
0
0
0
0
55
0
0
% E
% Phe:
0
0
0
10
10
0
0
0
10
10
0
37
0
10
0
% F
% Gly:
0
10
0
0
10
0
0
10
10
28
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
10
10
0
0
10
10
0
19
0
% I
% Lys:
10
0
0
10
0
19
0
10
0
28
0
10
10
19
10
% K
% Leu:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
55
% L
% Met:
0
0
0
10
0
0
0
10
10
0
0
0
0
0
10
% M
% Asn:
0
0
10
0
0
28
0
0
10
0
0
10
0
10
0
% N
% Pro:
0
0
64
0
0
0
10
0
0
10
0
10
0
10
0
% P
% Gln:
0
10
0
0
64
0
0
0
0
10
0
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
64
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
64
0
28
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
64
0
0
0
10
0
0
0
0
0
0
0
0
0
% T
% Val:
10
0
19
0
10
10
0
0
64
0
0
0
0
10
28
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
10
0
0
0
19
64
0
0
73
28
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _